Learning strategies during fear conditioning

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Learning strategies during fear conditioning.

This paper describes a model of fear learning, in which subjects have an option of behavioral responses to impending social defeat. The model generates two types of learning: social avoidance and classical conditioning, dependent upon (1) escape from or (2) social subordination to an aggressor. We hypothesized that social stress provides the impetus as well as the necessary information to stimu...

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Worrying Affects Associative Fear Learning: A Startle Fear Conditioning Study

A valuable experimental model for the pathogenesis of anxiety disorders is that they originate from a learned association between an intrinsically non-aversive event (Conditioned Stimulus, CS) and an anticipated disaster (Unconditioned Stimulus, UCS). Most anxiety disorders, however, do not evolve from a traumatic experience. Insights from neuroscience show that memory can be modified post-lear...

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Avoiding Negative Outcomes: Tracking the Mechanisms of Avoidance Learning in Humans During Fear Conditioning

Previous research across species has shown that the amygdala is critical for learning about aversive outcomes, while the striatum is involved in reward-related processing. Less is known, however, about the role of the amygdala and the striatum in learning how to exert control over emotions and avoid negative outcomes. One potential mechanism for active avoidance of stressful situations is postu...

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Contingency learning in human fear conditioning involves the ventral striatum.

The ability to detect and learn contingencies between fearful stimuli and their predictive cues is an important capacity to cope with the environment. Contingency awareness refers to the ability to verbalize the relationships between conditioned and unconditioned stimuli. Although there is a heated debate about the influence of contingency awareness on conditioned fear responses, neural correla...

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Cholinergic modulation during acquisition of olfactory fear conditioning alters learning and stimulus generalization in mice.

We investigated the role of cholinergic neurotransmission in olfactory fear learning. Mice receiving pairings of odor and foot shock displayed fear to the trained odor the following day. Pretraining injections of the nicotinic antagonist mecamylamine had no effect on subsequent freezing, while the muscarinic antagonist scopolamine significantly reduced freezing. To test whether cholinergic mani...

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ژورنال

عنوان ژورنال: Neurobiology of Learning and Memory

سال: 2009

ISSN: 1074-7427

DOI: 10.1016/j.nlm.2009.01.009